Učni načrt predmeta

Predmet:

Izbrana poglavja iz analizne kemije

Course:

Selected Chapters from Analytical Chemistry

Študijski program in stopnja / Study programme and level	Študijska smer / Study field	Letnik / Academic year	Semester / Semester
Ekotehnologije, 3. stopnja
/ 1 1

Vrsta predmeta / Course type

Izbirni

Univerzitetna koda predmeta / University course code:

EKO3-690

Predavanja Lectures	Seminar Seminar	Vaje Tutorial	Klinične vaje work	Druge oblike študija	Samost. delo Individ. work	ECTS
15	15			15	105	5

*Navedena porazdelitev ur velja, če je vpisanih vsaj 15 študentov. Drugače se obseg izvedbe kontaktnih ur sorazmerno zmanjša in prenese v samostojno delo. / This distribution of hours is valid if at least 15 students are enrolled. Otherwise the contact hours are linearly reduced and transfered to individual work.

Nosilec predmeta / Course leader:

prof. dr. Maja Ponikvar-Svet

Sodelavci / Lecturers:

Jeziki / Languages:

Predavanja / Lectures:

Slovene, English

Vaje / Tutorial:

Slovene, English

Pogoji za vključitev v delo oz. za opravljanje študijskih obveznosti:

Prerequisites:

Zaključena druga stopnja bolonjskega študija ali univerzitetni študijski program.

Completed Bologna second level or university type of undergraduate education.

Vsebina:

Content (Syllabus outline):

• Uvod v sodobno analizno kemijo: vloga in pomen analizne kemije: področja uporabe, razlika med analizno kemijo in kemijsko analizo, vloga analizne kemije v interdisciplinarnih raziskavah.
• Statistična obdelava podatkov in kemometrija: kalibracija in validacija, obdelava podatkov, multivariatne statistične metode
• Validacija analiznih metod in zagotavljanje kakovosti meritev: točnost, natančnost, ponovljivost, robustnost, meje zaznave in kvantifikacije; zagotavljanje kakovosti meritev, sledljivost meritev.
• Pregled nekaterih sodobnih analiznih metod:
• Spektroskopske analizne metode: UV/VIS, IR in atomska spektroskopija (AAS, ICP-OES)
• Elektrokemijske analizne metode: potenciometrija, kronopotenciometrija, polarografija, amperometrija, kulometrija in konduktometrija
• Kromatografske in separacijske tehnike: plinska in tekočinska kromatografija (GC, HPLC), kapilarna elektroforeza
• Masna spektrometrija
• Priprava in obdelava zahtevnih vzorcev
• Primeri uporabe analizne kemije v praksi: okoljske analize, farmacevtska in živilska kontrola, forenzična in klinična analitika, primeri iz industrijske prakse.

• Introduction to modern analytical chemistry: the role and importance of analytical chemistry, fields of application, the distinction between analytical chemistry and chemical analysis, and the role of analytical chemistry in interdisciplinary research.
• Statistical data treatment and chemometrics: calibration and validation, data processing, and multivariate statistical methods.
• Validation of analytical methods and quality assurance of measurements: accuracy, precision, repeatability, robustness, limits of detection and quantification; quality assurance of measurements and measurement traceability.
• Overview of selected modern analytical methods:
• Spectroscopic analytical methods: UV/VIS, IR, and atomic spectroscopy (AAS, ICP-OES)
• Electrochemical analytical methods: potentiometry, chronopotentiometry, polarography, amperometry, coulometry, and conductometry
• Chromatographic and separation techniques: gas and liquid chromatography (GC, HPLC), capillary electrophoresis
• Mass spectrometry
• Preparation and treatment of complex samples
• Examples of applications of analytical chemistry in practice: environmental analysis, pharmaceutical and food control, forensic and clinical analysis, and examples from industrial practice.

Temeljna literatura in viri / Readings:

D. A. Skoog, D. A. West, F. J. Holler and S. R. Crouch, Fundamentals of Analytical Chemistry, 10th Ed., Cengage Learning, Hempshire, 2021.
D. A. Skoog, F. J. Holler and S. R. Crouch, Principles of Instrumental Analysis, 7th Ed., Cengage Learning, Boston, 2018.
Evaluation of measurement data — Guide to the expression of uncertainty in measurement (GUM), 2008.
Quantifying Uncertainty in Analytical Measurement, EURACHEM / CITAC Guide CG 4, 3rd ed., 2012.
V.J. Barwick, S.L.R. Ellison, VAM Project 3.2.1 Development and Harmonisation of Measurement
Uncertainty Principles, Part (d): Protocol for uncertainty evaluation from validation data, 2000.data, 2000.

Cilji in kompetence:

Objectives and competences:

Po uspešno zaključenem predmetu bo študent sposoben:
• razumeti in uporabljati principe izbranih ključnih analiznih metod, s poudarkom na elektrokemijskih in spektrofotometričnih metodah ter CHNS elementni analizi;
• načrtovati in izvajati analitski postopek kot celoto, vključno z načrtovanjem analize, izvedbo meritev ter vrednotenjem in obdelavo analiznih rezultatov;
• razlikovati med naključnimi in sistematičnimi napakami ter razumeti načine njihovega obvladovanja v analizni kemiji;
• uporabljati pristope za obvladovanje naključnih in sistematičnih napak ter jih smiselno prenesti v raziskovalno in projektno delo;
• razumeti pomen metrologije, sledljivosti in zagotavljanja kakovosti meritev ter uporabljati te principe pri laboratorijskem in raziskovalnem delu;
• kritično presojati zanesljivost analiznih rezultatov z vidika točnosti, natančnosti in sledljivosti.

After successfully completing the course, the student will be able to:
• understand and apply the principles of selected key analytical methods, with emphasis on electrochemical and spectrophotometric methods, as well as CHNS elemental analysis;
• plan and carry out the entire analytical process, including planning the analysis, performing measurements, and evaluating and processing analytical results;
• distinguish between random and systematic errors and understand approaches to their control in analytical chemistry;
• apply strategies for managing random and systematic errors and effectively transfer them to research and project work;
• understand the importance of metrology, measurement traceability, and quality assurance, and apply these principles in laboratory and research work;
• critically assess the reliability of analytical results in terms of accuracy, precision, and traceability.

Predvideni študijski rezultati:

Intendeded learning outcomes:

Študenti bodo z uspešno opravljenimi obveznostmi pri predmetu pridobili:
• pregled sodobnih instrumentalnih tehnik analizne kemije ter razumevanje možnosti uporabe ključnih metod pri raziskovalnem in projektnem delu;
• razumevanje izbire in uporabe ustreznih analiznih metod glede na naravo problema, vrsto vzorca in zahtevano kakovost rezultatov;
• znanje načrtovanja analitskega postopka, od opredelitve problema do obdelave in interpretacije rezultatov;
• razumevanje osnov in principov metrologije, zagotavljanja kakovosti in sledljivosti meritev ter njihove uporabe v raziskovalnem delu.

Students who successfully complete the course requirements will acquire:
• an overview of modern instrumental techniques in analytical chemistry and an understanding of the applicability of key methods in research and project work;
• an understanding of the selection and application of appropriate analytical methods with respect to the nature of the problem, the type of sample, and the required quality of results;
• knowledge of planning the analytical procedure, from problem definition to data treatment and interpretation of results;
• an understanding of the fundamentals and principles of metrology, quality assurance, and measurement traceability, and their application in research.

Metode poučevanja in učenja:

Learning and teaching methods:

Predavanja, seminar, laboratorijske vaje

Lectures, Seminar work, Laboratory work

Načini ocenjevanja:

Delež v % / Weight in %

Assesment:

Seminar

Ustni izpit

Oral exam

Reference nosilca / Lecturer's references:

1.	PONIKVAR-SVET, Maja, LIEBMAN, Joel F. Analytical chemistry concerns of polynitrogen (NNN) species. V: RAPPOPORT, Zvi (ur.). Patai's chemistry of functional groups. Hoboken (NJ): Wiley. 2025, str. 1-37, doi: 10.1002/9780470682531.pat1022.
2.	PAVLOVIČ, Anja, JANŽIČ, Larisa, SRŠEN, Lucija, KOPITAR, Andreja Nataša, EDWARDS, Kathleen F., LIEBMAN, Joel F., PONIKVAR-SVET, Maja. Mononuclear aluminum-fluoride ions, AlFx(+/−) - study of plausible frameworks of complexes with biomolecules and their in vitro toxicity. Molecules 30 (2025) 389. doi: 10.3390/molecules30020389.
3.	LJUBEC BOŽIČEK, Barbara, ARAH, Bor, KUŠTER, Monika, NAGLIČ, Iztok, MARKOLI, Boštjan, PONIKVAR-SVET, Maja, EINFALT, Lara, ČEH, Miran, ALCANTARA MARINHO, Belisa. Electrocatalytic trends of different Cantor entropy alloys for alkaline and acidic hydrogen-evolution reactions. Mater. Today Commun. 41 (2024) 110876. doi: 10.1016/j.mtcomm.2024.110876.
4.	PAVLOVIČ, Anja, TAVČAR, Gašper, PONIKVAR-SVET Maja. Fluoride and aluminium in tea (Camellia sinensis L.) – Tea Quality indicators and risk factors for consumers. Molecules 28 (2023) 6396. doi: 10.3390/molecules28176396.
5.	HAN, Jianlin, KISS, Loránd, MEI, Haibo, REMETE, Attila Márió, PONIKVAR-SVET, Maja, SEDGWICK, Daniel Mark, ROMÀN, Raquel, FUSTERO, Santos, MORIWAKI, Hiroki, SOLOSHONOK, V. A. Chemical aspects of human and environmental overload with fluorine. Chemical Reviews 121 (2021) 4678–4742. doi: 10.1021/acs.chemrev.0c01263.