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Jožef Stefan
Postgraduate School

Jamova 39
SI-1000 Ljubljana

Phone: +386 1 477 31 00
Fax: +386 1 477 31 10


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Jožef Stefan International Postgraduate School invites to the lecture of Prof. Dr. Henning ULRICH (Departamento de Bioquimica, Instituto de Quimica Universidade de São Paulo, Brazil) entitled "Aptamer development for biosensorics and pharmaceutical applications", which will be on Wednesday, March 5th, 2014 at 1:00 p.m. at the IPS Lecture Hall N205, Jamova 39, Ljubljana.


Aptamers are small nucleic acid molecules capable of binding to a wide range of target molecules with high affinity and specificity. They have been developed and widely used not only as research tools, but also as biosensors, specific antagonists, and diagnostic markers and as protein purification platform for many pharmaceutical and clinical applications. Biochemical aspects of aptamer-target interactions will be explored and discussed why aptamers rival antibodies in target recognition. Moreover, we will also discuss aptamers whose binding parameters can be controlled on demand for diagnostic approaches and used as sensitive receptors in biosensorics. Aptamers have opened up exciting fields in basic and applied research of pharmaceutical and biotechnological interest.