MPŠ MP&Scaron MP&Scaron MP&Scaron Avtorji

Jo˛ef Stefan
Postgraduate School

Jamova 39
SI-1000 Ljubljana

Phone: +386 1 477 31 00
Fax: +386 1 477 31 10


Course Description

Sensor Systems


Ecotechnologies, third-level study programme


prof. dr. Aleksandra Lobnik


• Introduction to optical sensors for food quality
• To gain planning of specific sensors system for determinate analyte
• To identify possibility to use optical chemical sensors in real environment
• To widen knowledge from instrumental analytics to in-situ, on-line sensor micro and nano systems


• Introduction to sensor systems and their definition
• Chemical receptors
• Biochemical Receptors
• Review of most important polymer matrixes used in optical chemical/bio sensors which are used by analyte detection typical for food control
• Imobilization methods (electrostatic, covalent, doping methods...)
• UV/VIS absorption and luminiscence spectroscopy, IR spectroscopy
• Molecular imprinted polymers as sensors for analytes (covalent and electrostatic binding, polymer matrices, analyt, examples)
• Optical chemical sensors and optical fibres for in-situ, on-line detection
• Micro and nano sensors
• Examples of optical chemical sensors and their applications in food control
• Sensor validation using classical analytical methods (chromatographic…)
• Sensor systems and their transfer from the lab to the real environment

Seminar work:
• Literature overview in the area of optical chemical /biosensors for food quality control
• Seminar work preparation and their presentation

Course literature:

• O.S. Wolfbeis (ed.), Fiber Optic Chemical Sensors and Biosensors, Vols. I and II, CRC Press, Boca Raton, 1991.
• W. Göpel, J. Hesse, J. N. Zemel (eds.), Sensors - A Comprehensive Survey, VCH, Weinheim, 1991-1993.
• J. Janata, Principles of Chemical Sensors, Plenum Press, New York 1989.
• Lobnik, Sol-gels and other polymers used in optical chemical sensors, Boston, 2000

Significant publications and references:

1. LOBNIK, Aleksandra, KORENT UREK, Špela. Sol-gel based opto-chemical sensor for detection of diethyl chlorophosphate and method for its preparation : EP 2 678 673 (B1), 2016-06-08. Berlin, Germany: European Patent Office, 2016. 8 str. [COBISS.SI-ID 19608854]
2. NEDELJKO, Polonca, TUREL, Matejka, LOBNIK, Aleksandra. Postopek priprave in sestava senzorskega medija za optično zaznavanje agmatina : SI 24330 (A), 2014-09-30. Ljubljana: Urad RS za intelektualno lastnino, 2014. [4] str. [COBISS.SI-ID 18267158]
3. NEDELJKO, Polonca, TUREL, Matejka, KOŠAK, Aljoša, LOBNIK, Aleksandra. Synthesis of hybrid thiol-functionalized SiO[sub]2 particles used for agmatine determination. Journal of sol-gel science and technology, ISSN 0928-0707, [COBISS.SI-ID 19489046],
4. FRANČIČ, Nina, LYAGIN, Ilya V., EFREMENKO, Elena N., LOBNIK, Aleksandra. Hybrid sol-gel bio-films: influence of synthetic parameters on behaviour and performance of entrapped His[sub]6-tagged organophosphorus hydrolase. Journal of sol-gel science and technology, ISSN 0928-0707, [COBISS.SI-ID 18373654],
5. NEDELJKO, Polonca, TUREL, Matejka, LOBNIK, Aleksandra. Fluorescence-based determination of agmatine in dietary supplements. Analytical letters, ISSN 0003-2719. [Print ed.], 2015, vol. 48, iss. 10, str. 1619-1628, doi: 10.1080/00032719.2014.991962. [COBISS.SI-ID 18551062],
6. FRANČIČ, Nina, KOŠAK, Aljoša, LOBNIK, Aleksandra. Immobilisation of organophosphate hydrolase on mesoporous and Stöber particles. Journal of sol-gel science and technology, ISSN 0928-0707, Sep. 2016, vol. 79, iss. 3, str. 497-509. [COBISS.SI-ID 19635734],
7. FRANČIČ, Nina, BELLINO, Martin G., SOLER ILLIA, Galo, LOBNIK, Aleksandra. Mesoporous titania thin films as efficient enzyme carriers for paraoxon determination/detoxification: effects of enzyme binding and pore hierarchy in biocatalyst activity and reusability. Analyst, ISSN 0003-2654, 2014, vol. 139, iss. 12, str. 3127-3136.[COBISS.SI-ID 17536790],
8. WIDMER, Susanne, DORRESTIJN, Marko, CAMERLO, Agathe, KORENT UREK, Špela, LOBNIK, Aleksandra, HOUSECROFT, Catherine E., CONSTABLE, Edwin C., SCHERER, Lukas J. Coumarin meets fluorescein: a Förster resonance energy transfer enhanced optical ammonia gas sensor. Analyst, ISSN 0003-2654, 28 Jul. 2014, vol. 139, iss. 17, str. 4335-4342. [COBISS.SI-ID 18048278],
9. FRANČIČ, Nina, KOŠAK, Aljoša, LYAGINI, Ilya V., EFREMENKO, Elena N., LOBNIK, Aleksandra. His[sub]6-OPH enzyme-based bio-hybrid material for organophosphate detection. Analytical and bioanalytical chemistry, ISSN 1618-2642, 2011, vol. 401, no. 8, str. 2631-2638, doi: 10.1007/s00216-011-5336-1. [COBISS.SI-ID 15269398],
10. KORENT UREK, Špela, LOBNIK, Aleksandra, MOHR, G. J. Sol-gel-based optical sensor for the detection of aqueous amines. Analytical and bioanalytical chemistry, ISSN 1618-2642, Apr. 2007, vol. 387, no. 8, str. 2863-2870. [COBISS.SI-ID 11135254]


Project with public presentation (50%)
Written exam (50%)

Students obligations:

Project with public presentation
Written exam