MPŠ MP&Scaron MP&Scaron MP&Scaron Avtorji

Jožef Stefan
Postgraduate School

Jamova 39
SI-1000 Ljubljana

Phone: +386 1 477 31 00
Fax: +386 1 477 31 10


Course Description

Mass Occurrence of Toxic Phytoplankton in the Environment


Ecotechnologies, third-level study programme


prof. dr. Bojan Sedmak


The understanding of environmental problems, the negative impact of pollution, the possible negative effects of careless interventions and the response of organisms on high speed changes in the environment.
The candidate is acquainted with ecotoxicological and toxinological methods, field and laboratory work.


The course is divided in several themes in the field of mass occurrence of toxic organisms:
- Ecological factors;
- Toxins and their biological activity;
- Neurotoxins;
- Neurotoxic amino acids;
- Alkaloids;
- Linear and cyclic peptides;
- Endotoxins;
- Ecotoxicology;
- Toxins and their biological activities;
- HAB – Harmful algal blooms;
- CyanoHAB – Harmful cyanobacterial blooms;
- Monitoring and legislation.

Course literature:

Chorus I., Bartram J (eds.): Toxic cyanobacteria in water. A guide to their public health consequences, monitoring and management. WHO, Spon Press, New York, 1999.

Botana L.M.: Seafood and freshwater toxins. Pharmacology, physiology and detection, Taylor and Francis, 2005.

Gilbert J., Senyuva H.,Z: Bioactive compounds in food. Blachwell Pub.Ltd., UK, 2008

Sedmak B.: Cianobakterije in njihovi toksini. Kdo so, kje jih najdemo in kako delujejo? NIB, Ljubljana, 2011.

Sedmak B et al.: The biological role of cyclic hepatotoxic and non-hepatotoxic cyanopeptides and its ecological consequences. In: Ecotoxicology Research Developments, Ed.:Santos EB, Nova Science Pub., New York, 2009.

Coastal and Estuarine Studies. Eutrophication in coastal marine ecosystems. Eds.: Jorgensen BB and Richardson K, American Geophysical Union, Washington, DC, 1996.

Premazzi G., Volterra L.: Microphyte toxins. A manula for toxin detection, environmental monitoring and therapies to counteract intoxications. Commission of European Communities, Luxembourg, 1993.

Review articles on selected topics.

Significant publications and references:

SEDMAK, Bojan, CARMELI, Shmuel, ELERŠEK, Tina. " Non-toxic" cyclic peptides induce lysis of cyanobacteria-an effective cell population density control mechanism in cyanobacterial blooms. Microb. ecol., 2008, issue 2, vol. 56, str. 201-209., doi: doi:10.1007/s00248-007-9336-9. [COBISS.SI-ID 1798479], [JCR]
SEDMAK, Bojan, ELERŠEK, Tina, GRACH-POGREBINSKY, Olga, CARMELI, Shmuel, SEVER, Nataša, LAH TURNŠEK, Tamara. Ecotoxicologically relevant cyclic peptides from cyanobacterial bloom (Planktothrix rubecens) - a threat to human and environmental health = Ekotoksikološko pomembni ciklični peptidi iz cianobakterijskega cveta (Planktothrix rubescens) - grožnja človeškemu in okoljskemu zdravju. Radiol. oncol. (Ljubl.), 2008, vol. 42, no 2, str. 102-113, doi: 10.2478/v10019-088-0001-9. [COBISS.SI-ID 1861199], [JCR]
SEDMAK, Bojan, CARMELI, Shmuel, POMPE NOVAK, Maruša, TUŠEK-ŽNIDARIČ, Magda, GRACH-POGREBINSKY, Olga, ELERŠEK, Tina, ŽUŽEK, Monika C., BUBIK, Anja, FRANGEŽ, Robert. Cyanobacterial cytoskeleton immunostaining: the detection of cyanobacterial cell lysis induced by planktopeptin BL1125. J. plankton res., 2009, vol. 31, no. 11, str. 1321-1330., doi: 10.1093/plankt/fbp076. [COBISS.SI-ID 2070607], [JCR]


Oral exam (60 %)
presentation and defence of the seminar (40 %)

Students obligations:

Attend the lectures, contribute to class discussions, prepare the seminar and ist defence.