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The determination of genotoxicity is an important element in the safety assessment of various substances, with the purpose of preventing a number of chemicals from affecting human health. Genotoxicity testing is required for all classes of chemicals, drugs and biological agents, which can lead to a wide range of diseases, …

Apoptosis is an innate mechanism by which a multicellular organisms eliminates unwanted, damaged and potentially harmful cells. During apoptosis inflammation of the surrounding tissues is prevented. Defects in an apoptotic signaling can lead to numerous pathological conditions. Apoptosis is mediated through two main pathways, the extrinsic or the death receptor …

Feature ranking is the machine learning task of inducing an ordering of features in a given dataset according to some notion of relevance. We consider the feature ranking task in the context of supervised learning, where the notion of feature relevance is defined with respect to a target concept. Feature …

Radon and its progeny play an important role contributing to the dose of radiation which a person receives from all natural sources of ionizing radiation. This is one of the reasons why this problem has been of great interest, as a result of which an increased number of scientific works …

Selenium (Se) has been demonstrated to be an essential trace element for maintenance of animal and human health. Se is incorporated into proteins to make selenoproteins, which are important antioxidant enzymes. The antioxidant properties of selenoproteins help to prevent cellular damage caused by radicals. Radicals are natural by-products of oxygen …

Microarrays are at the center of a revolution in biotechnology, allowing researchers to simultaneously monitor the expression of tens of thousands of genes. The final aim of a typical microarray experiment is to find a molecular explanation for a given macroscopic observation (e.g., which pathways are affected by the loss …