Search Results (14)
Contribution to understanding of the mechanism of amyloid fibril formation and its effects on the cell
The presence of insoluble amyloid aggregates in various human tissues correlates with the development of many human disorders (amyloidoses), including neurodegenerative diseases. Deposition of the aggregated misfolded proteins in the brain, where aggregates can be localized extracellularly or intracellularly, is the main characteristic of Alzheimer's, Parkinson's, Huntington's, prion diseases and …
The synthesis and characterization of glass–ceramics based on ternary system MgO-B2O3-SiO2
The past fifteen years has seen the rapid development of various wireless communication devices, which operate at microwave or milimeterwave frequencies (mobile phones, wireless local-area networks (LAN), Bluetooth, etc.). At the same time, this progress has stimulated the development of new materials and process technologies, which enable the size reduction …
Speciation of aluminium in human serum by CIM® (Convective Interaction Media) monolithic chromatography and mass spectrometry
The toxicity, biological availability and mobility of aluminium (Al) depend on its chemical form. In order to understand toxicity and transport of Al in human body it is important to identify and quantify Al species present in human serum. This led to the development of sensitive and selective analytical methods …
Expression and characterization of cysteine peptidases metacaspases and autophagins from the parasite Trypanosoma cruzi
Cysteine peptidases have been demonstrated to be important virulence factors of protozoan parasites, including Trypanosoma cruzi. With genome sequence determination the existence of several novel families of cysteine peptidases can be envisioned in this parasite. We focused on two families, metacaspases from the clan CD and autophagins (or Atg4 proteases) …