The problem of structure determination of membrane proteins is addressed with a new combination of site-directed spin labelling (SDSL) electron paramagnetic resonance (EPR) spectroscopy and structure modelling of a protein and its conformational spaces. This new approach is aimed at structural characterization of membrane proteins and intrinsically disordered proteins. In …
Mercury (Hg) pollution has been investigated in the area of the Idrija mercury mine, Slovenia, where the second largest mercury mine in the world operated for more then 500 years. Although the production of mercury at the Idrija mercury mine stopped in 1994, centuries of mining and ore processing operations …
Neutron activation analysis (NAA) is an analytical method used for determination of the elemental mass fractions in different samples. It is based on the measurement of characteristic radiation, usually γ-rays, emitted from radionuclides formed through the process of neutron irradiation of the target element. The k0-NAA method is an NAA …
Microarrays are at the center of a revolution in biotechnology, allowing researchers to simultaneously monitor the expression of tens of thousands of genes. The final aim of a typical microarray experiment is to find a molecular explanation for a given macroscopic observation (e.g., which pathways are affected by the loss …