Plasma-assisted Bio-sensing Techniques
5
ECTS Credits
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Goals
Objectives: - Evaluation of plasma technologies for surface modification of biosensors, - Analysis of quartz crystal microbalance signal, - Evaluation of adsorption mechanisms for biomaterials, - Analysation of fragmentized macromolecules spectra and evaluation of microelements and specific functional groups, - Synthesis of biopolymers with reactive neutral gaseous radicals. Competences: - Selecting optimal sensors for specific macromolecules, proteins, blood platelets and microvesicles and ability to solve specific scientific and/or technological problems, - Identification and evaluation of adhesion kinetics and properties of adsorbed films, - Prediction and explanation of proteins, blood platelets and macromolecules behaviour upon interaction with selected solid materials.
Curriculum
- Advanced micro- and nano- structured sensors suitable for detection of blood proteins, platelets as well as viruses and virus-like macromolecules.
- Limitations of existing sensors and current trends in development of novel sensors.
- Application of quartz microbalance technique for probing adhesion of thin biological films.
- Spectrometry of biomolecular fragments for detection of microelements as well as specific functional groups.
- Application of non-equilibrium gases for modification of biopolymers to allow specific adsorption and conformation of macromolecules.
Obligations
Completed second cycle studies in natural sciences or engineering or completed second cycle studies in other fields with proven knowledge of fundamentals in the field of this course (certificates, interview).Examination
Literature and references
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