Meshless methods are becoming increasingly popular in computational mechanics and engineering. Their main feature is the ability to manage complex geometries while avoiding the often tedious process of mesh generation required by the traditional methods. Various meshless approximations of linear differential operators appearing in the governing problem have been proposed …
Cysteine peptidases have been demonstrated to be important virulence factors of protozoan parasites, including Trypanosoma cruzi. With genome sequence determination the existence of several novel families of cysteine peptidases can be envisioned in this parasite. We focused on two families, metacaspases from the clan CD and autophagins (or Atg4 proteases) …