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Advanced glioblastoma models to study tumour microenvironment and to support novel glioblastoma therapeutics

Author(s): Bernarda Majc (Author), Tamara Lah Turnšek (Supervisor), Metka Novak (Co-Supervisor)

Year: 2023

Type: Doctoral dissertation

Glioblastoma (GB) is the most common and aggressive primary tumour of the central nervous system. Despite maximal possible surgical resection of the tumours and aggressive treatment regimens with radiotherapy and chemotherapy, patient overall survival is less than 2 years, as patients eventually develop resistance to therapy, resulting in recurrent tumours. …