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Computational investigation of protein-RNA interactions detected by CLIP, their specificity and dynamics in embryonic development

Author(s): Klara Kuret (Author), Jernej Ule (Supervisor), Miha Modic (Co-Supervisor)

Year: 2024

Type: Doctoral dissertation

RNA molecules dynamically interact with RNA-binding proteins (RBPs), which control various aspects of RNA fate, such as its processing, localisation, and stability. Intricate networks of protein-RNA interactions thereby regulate gene expression and have a profound effect on downstream cellular processes. Most RBPs recognise specific motifs on their bound RNAs, characterised …