Latest Academic Works
Synthesis and investigation of organofluorosilicate and organofluorogermanate species
Fluorine, though abundant on Earth, is not readily available in a form suitable for organic synthesis. While fluoride salts like fluorite exist, they have limited reactivity due to solubility properties. Converting fluorite to hydrofluoric acid (HF) or fluorine gas (F2) increases reactivity but introduces significant safety concerns due to the …
In silico approach to understanding the mechanism of action and chemical toxicity prediction on human aromatase enzyme
Aromatase is an enzyme member of the cytochrome P450 superfamily coded by the CYP19A1 gene. Its main biological function in humans is the conversion of androgens into estrogens, transforming androstenedione into estrone and testosterone into estradiol. This enzyme is present in several tissues, and it has a key role in …
Discrete aluminium compounds – towards a soluble aluminium trifluoride
In the past, the search for soluble aluminium trifluoride (AlF3) led to the discovery of organoaluminium compounds (AlR3) and organoaluminium fluorides. However, suitable methods for the introduction of fluorine into AlR3 are still scarce, making the discrete AlF3 and organoaluminium fluoride compounds rare. Our investigation of the reactivity of cyclic …