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Latest Academic Works

Quantitative imaging of cisplatin in tumour samples by laser ablation inductively coupled plasma mass spectrometry

Author(s): Stefan Marković (Author), Janez Ščančar (Supervisor), Janja Vidmar (Co-Supervisor)

Year: 2022

Type: Doctoral dissertation

Medicine relies on imaging techniques such as ultrasound, magnetic resonance, computed tomography and histopathological image analysis because they provide valuable data needed for the diagnosis and treatment of diseases and injuries. Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) is often used in research and for the advanced diagnosis and …

In silico approaches to understand and predict the ligand-binding interactions of the human P-glycoprotein (ABCB1) membrane transporter

Author(s): Liadys Mora Lagares (Author), Marjana Novič (Supervisor), Emilio Benfenati (Co-Supervisor)

Year: 2021

Type: Doctoral dissertation

The P-glycoprotein (P-gp) is responsible for the elimination of a wide variety of substances from the cell, thus it is thought to play an important role in detoxification functions. The P-gp also affects the ADMET (absorption, distribution, metabolism, excretion, and toxicity in pharmacokinetics) properties of drugs. It is involved in …