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Development and application of a non-targeted screening workflow for chemical exposure assessment in human biomonitoring and related studies

Author(s): Žiga Tkalec (Author), Tina Kosjek (Supervisor)

Year: 2022

Type: Doctoral dissertation

Human exposure to environmental stressors is widespread. Highly dynamic, these chemical, physical and social factors, collectively termed as the exposome, interact with internal factors such as genetics, sex, gut microbiome and general health status, and dictate susceptibility and risk for an onset of diseases. Human exposure to the chemicals is …

Targeted analysis of organic contaminants, exposure assessment, and vulnerability of populations to hazardous compounds

Author(s): Agneta Annika Runkel (Author), Milena Horvat (Supervisor), Tina Kosjek (Co-Supervisor)

Year: 2022

Type: Doctoral dissertation

From the moment of conception until death, humans are exposed to chemicals at varying intensities and frequencies. While an individual’s level of resilience is commonly high enough to tolerate these kinds of stressors, specific exposures or genetic predispositions can lower it. Therefore, the assessment of chemical exposure, the development of …