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Cathepsin cleavage of epidermal growth factor receptor (EGFR) affects signaling pathways of cancer cells

Author(s): Marija Grozdanić (Author), Marko Fonović (Supervisor)

Year: 2023

Type: Doctoral dissertation

Epidermal growth factor receptor (EGFR) belongs to the ErbB family of receptor tyrosine kinases and plays an essential role in cell differentiation, migration, proliferation, and metabolism. Alterations in EGFR signalling were found in a number of cancers like lung, breast, colorectal cancer and gliomas, shown to be more aggressive and …

Microstructural analysis and evaluation OF W and W/W2C composites for fusion application

Author(s): Andreja Šestan (Author), Miran Čeh (Supervisor), Saša Novak Krmpotič (Co-Supervisor)

Year: 2023

Type: Doctoral dissertation

Fusion technology has a great potential to safely provide an inexhaustible quantity of electricity without producing greenhouse gases and minimal hazardous waste compared to conventional energy sources, such as nuclear power plants. For materials intended for fusion plasma-facing applications, the essential properties are structural stability at elevated temperature, adequate thermal …

Ostanki bisfenolov v vodnem okolju: pojavnost in kroženje

Author(s): Ana Kovačič (Author), Ester Heath (Supervisor), Tina Kosjek (Co-Supervisor)

Year: 2021

Type: Doctoral dissertation

Bisphenols are a group of industrial chemicals increasingly recognized as contaminants of emerging concern because of their presence in the environment and endocrine disrupting effects. They are used in the production of polycarbonate plastic, epoxy resins and thermal paper, in most cases without restriction. The global exception is bisphenol A, …

Sintering and phase transition behaviour of sodium niobate

Author(s): Jurij Koruza (Author), Barbara Malič (Supervisor), Tadej Rojac (Co-Supervisor)

Year: 2013

Type: Doctoral dissertation

Sodium niobate (NaNbO3) is the end member of several alkaline niobate-based solid solutions, which represent an important group of environment-friendly lead-free piezoceramics. Even though alkaline niobates are of considerable technological importance, problems in obtaining high densities and a fine-grained microstructure are still reported and not much is known about the …

Migration of critical radionuclides in the area of former uranium mine Žirovski vrh

Author(s): Marko Štrok (Author), Borut Smodiš (Supervisor)

Year: 2011

Type: Doctoral dissertation

A study of the migration of critical radionuclide in the area of the former uranium mine of Žirovski vrh in Slovenia was performed. Critical natural radionuclides are defined as the long-lived natural radionuclides from the uranium-radium decay chain, which are 238U, 234U, 230Th, 226Ra, 210Pb and 210Po. In the area …