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Latest Academic Works

An intelligent cognitive system for computational psychotherapy with a conversational agent for attitude and behavior change in stress, anxiety and depression

Author(s): Tine Kolenik (Author), Matjaž Gams (Supervisor), Günter Schiepek (Co-Supervisor)

Year: 2023

Type: Doctoral dissertation

The increasing prevalence of mental health issues worldwide has amplified the significance of computational psychotherapy, which includes creating computational tools for the mental healthcare and tools to support existing mental health professionals. This work presents a computational psychotherapy system that predicts and forecasts mental health issues in users, and utilizes …

Advanced glioblastoma models to study tumour microenvironment and to support novel glioblastoma therapeutics

Author(s): Bernarda Majc (Author), Tamara Lah Turnšek (Supervisor), Metka Novak (Co-Supervisor)

Year: 2023

Type: Doctoral dissertation

Glioblastoma (GB) is the most common and aggressive primary tumour of the central nervous system. Despite maximal possible surgical resection of the tumours and aggressive treatment regimens with radiotherapy and chemotherapy, patient overall survival is less than 2 years, as patients eventually develop resistance to therapy, resulting in recurrent tumours. …

Speciation of ruthenium-based candidate drugs for cancer treatment and copper as a potential biomarker for cancer diagnosis in human serum

Author(s): Katarina Marković (Author), Radmila Milačič (Supervisor)

Year: 2022

Type: Doctoral dissertation

According to the World Health Organization (WHO), cancer represents the second leading cause of mortality, with almost 10 million deaths in 2020. A broad spectra of cancer treatments are being developed, among them are metal-based drugs. Consistent with the available data, platinum (Pt)-based chemotherapeutics are still widely used to treat …