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Role and significance of cysteine cathepsins in different models of apoptosis

Author(s): Ana Petelin (Author), Boris Turk (Supervisor)

Year: 2009

Type: Doctoral dissertation

Programmed cell death is a highly organized process by which multicellular organisms eliminate damaged, superfluous and potentially harmful cells. Apoptosis is the most studied form of programmed cell death. It is characterized by typical morphological and biochemical changes which are a consequence of activation of cysteine proteases, caspases. Apoptosis is …