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Regulation of cysteine proteases cathepsins B, S and K and their role in inflammatory processes

Author(s): Urška Požgan (Author), Boris Turk (Supervisor)

Year: 2010

Type: Doctoral dissertation

Proteases are responsible for enzymatic cleavage of peptide bonds, which is a basic requirement for completion of diverse biological processes.The proteolytic activity of proteases must be rigorously controlled to avoid inappropriate degradation of proteins. Imbalance in regulation of proteolytic activity can be found in a wide range of diseases. Degradation …