Search Results (4)
Genetic variability and lead exposure biomarkers
The thesis investigates associations between the biomarkers of lead (Pb) exposure (and mercury (Hg), where applicable) and genetic variability in in vulnerable populations, including pregnant women and their newborns from Italy, Slovenia, and Croatia, as well as Slovenian men of reproductive age. The research utilizes data from the Public Health …
Speciation of ruthenium-based candidate drugs for cancer treatment and copper as a potential biomarker for cancer diagnosis in human serum
According to the World Health Organization (WHO), cancer represents the second leading cause of mortality, with almost 10 million deaths in 2020. A broad spectra of cancer treatments are being developed, among them are metal-based drugs. Consistent with the available data, platinum (Pt)-based chemotherapeutics are still widely used to treat …
Targeted analysis of organic contaminants, exposure assessment, and vulnerability of populations to hazardous compounds
From the moment of conception until death, humans are exposed to chemicals at varying intensities and frequencies. While an individual’s level of resilience is commonly high enough to tolerate these kinds of stressors, specific exposures or genetic predispositions can lower it. Therefore, the assessment of chemical exposure, the development of …
Organic geochemistry of stratified eutrophic alpine lakes (Lake Bled)
The identification and quantification of organic compounds present in the environment is a major area of application in modern analytical chemistry. However, it is still scarcely recognized that, in addition to the chemical identity and concentration of organic compounds, there is more information to be found about their source and …