The process of protein folding describes the transition by which an unordered polypeptide chain attains its functional native three-dimensional structure. A detailed understanding of the principles which govern the protein folding, such as conformational preferences of amino acid residues, the neighbour residue effect and the solvent effects, remains an important …
The identification and quantification of organic compounds present in the environment is a major area of application in modern analytical chemistry. However, it is still scarcely recognized that, in addition to the chemical identity and concentration of organic compounds, there is more information to be found about their source and …
Nuclear fusion offers a prospect of a safe, economical and environmentally friendly source of energy. For the advanced concepts of nuclear fusion, SiC-based fibre reinforced composites were proposed as a structural material for the first wall of the reactor vessel, enabling higher operating temperatures and efficiencies. Already developed techniques for …
Sodium niobate (NaNbO3) is the end member of several alkaline niobate-based solid solutions, which represent an important group of environment-friendly lead-free piezoceramics. Even though alkaline niobates are of considerable technological importance, problems in obtaining high densities and a fine-grained microstructure are still reported and not much is known about the …
Radon (222Rn, half-life 3.82 days) is a natural radioactive noble gas which originates from the radioactive decay of radium (226Ra) in the Earth's crust. It is a known hazard to humans, due to its radioactivity. Moreover, radon can also be used as a versatile tool in geophysical research. In order …
Buildings are complex systems as external factors are linked to, and have an effect on the characteristics of a building. In this dissertation, the focus is on the connection between external factors and the building’s characteristics, which have an impact on the living conditions, durability and energy efficiency of a …
The aim of the present thesis was to examine the effect of normobaric hypoxic confinement on selected metabolic responses. This was investigated in two separate studies: Study I investigated the effect of normobaric hypoxia, as frequently used by athletes for altitude training, on metabolism. The metabolic responses were assessed in …
The aging of bone tissue, bone defects that form during the removal of cysts, tumours, genetic defects and other bone‐tissue‐related diseases, together with demands for a better quality of life, mean a requirement for materials, artificial or autogenous, that will have a long functionality and survivability under the body’s environmental …
Heterogeneous reactions of trifluoromethane CHF3 with solid xerogel oxides, alkali hydroxides and carbonates were investigated under static and dynamic conditions and at moderate temperatures. In all cases, main reaction is fluorination characterised by a complete decomposition (mineralisation) of the fluorinating agent, CHF3, and the formation of the solid metal fluorides. …
In this thesis we address the problem of learning various types of decision trees from timechanging data streams. In particular, we study online machine learning algorithms for learning regression trees, linear model trees, option trees for regression, multi-target model trees, and ensembles of model trees from data streams. These are …