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Presented work is a study of magnetic iron oxide (referred to as spinel) coating synthesis. The coatings were synthesized on the surfaces of selected core nanoparticles with heterogeneous nucleation during the co-precipitation of the Fe3+/Fe2+ ions. The work is divided into three parts. The first part comprise the synthesis of …

The thesis addresses the development of novel knowledge discovery scenarios in a modern data mining platform by utilising principles of service-oriented architecture with web services, interactive scientific workflows, knowledge discovery ontologies and automated construction of data mining workflows. We present the developed Orange4WS platform which upgrades Orange, a mature open-source …

The aging of bone tissue, bone defects that form during the removal of cysts, tumours, genetic defects and other bone‐tissue‐related diseases, together with demands for a better quality of life, mean a requirement for materials, artificial or autogenous, that will have a long functionality and survivability under the body’s environmental …

The KNN solid solution was prepared from pre-synthesized binary compounds of, sodium and potassium niobate in a 1/1 molar ratio. The KNG sintering aid was prepared by homogenizing the pre-reacted binary mixtures of alkaline reagents and germanium oxide with the Na/Ge = 1/1 and K/Ge = 1/1 molar ratios. The …

The presence of steroid estrogens in the environment has been studied intensively for two decades because of their possible deleterious effects on living organisms at very low (ng/L) concentrations. To determine concentrations of steroid estrogens and the estrogenic potential of environmental samples, sophisticated and sensitive analytical techniques as well as …

In this thesis we present the development of the device for the removal of carbon deposits in fusion reactors. Amorphous hydrogenated carbon deposits (a-C:H) represent a major problem for smooth operation of future fusion reactors with divertors containing carbon tiles, because they cause retention of radioactive tritium. There are techniques …

Major histocompatibility complex (MHC) class II molecules are polymorphic cell surface glycoproteins expressed only on the surface of the professional antigen presenting cells and they play a crucial role in the adaptive immune responses. MHC class II molecules undergo a very complex maturation process. They are synthesized in the endoplasmic …

The research work presented in this thesis considers the development of new biocompatible surfaces that are able to control the adhesion of specific proteins responsible for the development of neurodegenerative diseases such as Creutzfeldt–Jakob, Alzheimer, Parkinson and Lewis body disease. Our approach was focused on problems prior to the detection …

The presence of insoluble amyloid aggregates in various human tissues correlates with the development of many human disorders (amyloidoses), including neurodegenerative diseases. Deposition of the aggregated misfolded proteins in the brain, where aggregates can be localized extracellularly or intracellularly, is the main characteristic of Alzheimer's, Parkinson's, Huntington's, prion diseases and …

The main purpose of this thesis is to describe the inhomogeneous phase of a layered system. The phase is the result of the competition between attractive interactions and the long range Coulomb repulsive force (LRCF). In order to achieve this, two different strategies are applied. The first is within the …