The potential toxicity of nanoparticles in our environment and consumer products is currently determined by costly and timely animal-based testing, which limits the rate of nanoparticle testing, causing a desperate need for alternative testing strategies. A promising alternative – mechanism-based prediction – employs a set of high-throughput cell-based tests that …
Vascular grafts made of polyethyleneterephthalate (PET) polymers have successfully replaced large-diameter blood vessels, but the long-term performance of small-diameter (< 6 mm) vascular grafts is still disappointing. The main problem is insufficient biocompatibility of polymer surface with blood, which causes complications after implementation; such as thrombosis or restenosis. These complications …