Search Results (39)
Phase separation in a 2D charged system
The main purpose of this thesis is to describe the inhomogeneous phase of a layered system. The phase is the result of the competition between attractive interactions and the long range Coulomb repulsive force (LRCF). In order to achieve this, two different strategies are applied. The first is within the …
Synthesis and Characterization of Bi12SiO20 Thin Films Prepared by Sol-gel Method
The sillenites Bi12MO20 (M = Si, Ge, Ti, Pb, Mn, B1/2P1/2) have been recognised as promising bulk materials for electronic applications because their dielectric properties (5.5 GHz: ε = 37.4 - 41, τf = -19 – (-84) ppm/K, Q x f = 800 - 8100 and Tsin = 680 - …
Comparative View into Protease - Inhibitor Interaction
Interactions between macromolecules are the basic events of life. Their characterization is thus a key to understanding the physiology and the underlying specificity of these events. Not only understanding of the final states (where the molecules get closest together), also understanding of the course of approach is mandatory to gain …
Colloidal Interactions and Novel Colloidal Structures in Thin Nematic Layers
The thesis presents experimental studies of colloidal interactions and novel colloidal structures in confined nematic liquid crystal using optical tweezers. Liquid crystal colloids are a novel class of composite materials with well-controlled periodic structures in the nanometer and micrometer ranges. Moreover, they also posses novel mechanical, optical and rheological properties, …
Role of Cysteine Cathepsins in the Processing, Activation and Inactivation of Perforin
Natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) recognize virus-infected or malignant transformed cells and destroy them through two independent mechanisms. Apoptotic target-cell death can be triggered by the engagement of death-receptors or by the release of cytotoxic granules. Cytotoxic granules gather at the site of contact between the …
Regulation of cysteine proteases cathepsins B, S and K and their role in inflammatory processes
Proteases are responsible for enzymatic cleavage of peptide bonds, which is a basic requirement for completion of diverse biological processes.The proteolytic activity of proteases must be rigorously controlled to avoid inappropriate degradation of proteins. Imbalance in regulation of proteolytic activity can be found in a wide range of diseases. Degradation …
Plasma sterilization of microorganisms
The sterilization efficiency of oxygen plasma was studied. Plasma was created in pure oxygen with an inductively coupled radiofrequency discharge. The discharge power was estimated to about 180 W. Plasma parameters were measured with a double Langmuir probe and a catalytic probe. Plasma parameters depended on pressure in the discharge …
Analysis of bacteria damages caused by treatment with oxygen plasma particles
The possible mechanisms for destruction of two types of bacteria with oxygen radicals were studied. Samples consisting of standard ATCC strains of Gram – positive bacteria Staphylococcus aureus and Gram – negative bacteria Escherichia coli were obtained. Bacteria were cultivated according to the standard procedures and fixed on substrates of …
Modular gene dynamics and network theory at mesoscopic scale
Complex dynamical systems are often modeled as networks, with nodes representing dynamical units which interact through the network’s links. Gene regulatory networks, responsible for the production of proteins inside a cell, are an example of system that can be described as a network of interacting genes. The behavior of a …