Search Results (7)
Pre-processing of heterogeneous data streams for internet of things applications
The rapid evolution of sensor technologies, particularly within the Internet of Things (IoT) domain, has led to an era dominated by massive real-time data flows. This transition resulted in the need for novel data processing methodologies that facilitate the shift from traditional offline batch analytics to agile real-time predictions and …
Validation of peptides as protein substrate models for specificity studies of cysteine cathepsins
Cysteine cathepsins are endosomal proteases that are involved in lysosomal protein degradation. Additionally, they engage in specific biological processes, like bone degradation (CatK), antigen presentation (CatS) and pro-hormone processing (CatV and CatL). Their enhanced activity was described in numerous pathological states, like cancer and viral activation, which made them promising …
Processing of heavy-rare-earth-lean Nd-Fe-B permanent magnets for high-temptrature applications
Permanent magnets are materials that generate a magnetic field in free space without electricity or other external energy sources. They are essential components of modern technologies, used in many electrical devices. Nowadays, they are included in technology for renewable sources of energy, such as electrical vehicles, generators and wind turbines. …
Predicting the dynamics of spatio-temporal systems based on heterogeneous data sources
As urbanisation continues to be a trend, in which centralisation of the population into cities is still growing, the importance of intelligent solutions in mobility is in high demand. Likewise, with the integration of renewable energies into all levels of the electrical grid system and the increasing amount of heavy …
Production and characterization of MHC class II invariant chain complex
Major histocompatibility complex (MHC) class II molecules are polymorphic cell surface glycoproteins expressed only on the surface of the professional antigen presenting cells and they play a crucial role in the adaptive immune responses. MHC class II molecules undergo a very complex maturation process. They are synthesized in the endoplasmic …
Moderately porous zirconia ceramics for dental applications
This doctoral thesis describes the preparation of moderately porous Y-TZP ceramics with improved flexural strength. The main field of application is dentistry, where the elastic mismatch between the Y-TZP material and tooth substance influences the survival rate of fixed partial dentures (FPDs). By introducing porosity into the bulk samples a …
Role of Cysteine Cathepsins in the Processing, Activation and Inactivation of Perforin
Natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) recognize virus-infected or malignant transformed cells and destroy them through two independent mechanisms. Apoptotic target-cell death can be triggered by the engagement of death-receptors or by the release of cytotoxic granules. Cytotoxic granules gather at the site of contact between the …