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Development and application of molecularly imprinted polymers for selected antidepressants and studies of their environmental fate

Author(s): Tjaša Gornik (Author), Tina Kosjek (Supervisor), Ester Heath (Co-Supervisor)

Year: 2022

Type: Doctoral dissertation

This thesis focuses on the fate of chosen antidepressants in the environment. Studied compounds belong to the class of selective serotonin reuptake inhibitors. Reportedly they do not completely mineralize by existing water treatment processes and their residues cause unwanted toxic effects in aquatic organisms. However, to date, insufficient information has …

Annotation of semi-polar organic contaminants by using gas chromatography coupled to mass spectrometry and machine learning

Author(s): Milka Ljoncheva (Author), Tina Kosjek (Supervisor), Sašo Džeroski (Co-Supervisor)

Year: 2022

Type: Doctoral dissertation

Contaminants of emerging concern (CECs), representing a subgroup of organic compounds of natural or synthetic origin, and their degradation and transformation products (TPs), with potentially harmful effects on humans, biota, and the environment, are the eco-exposome (EE) constituents of utmost importance. Their identification, quantification, and continued investigation into their environmental …

Development and application of a non-targeted screening workflow for chemical exposure assessment in human biomonitoring and related studies

Author(s): Žiga Tkalec (Author), Tina Kosjek (Supervisor)

Year: 2022

Type: Doctoral dissertation

Human exposure to environmental stressors is widespread. Highly dynamic, these chemical, physical and social factors, collectively termed as the exposome, interact with internal factors such as genetics, sex, gut microbiome and general health status, and dictate susceptibility and risk for an onset of diseases. Human exposure to the chemicals is …

Targeted analysis of organic contaminants, exposure assessment, and vulnerability of populations to hazardous compounds

Author(s): Agneta Annika Runkel (Author), Milena Horvat (Supervisor), Tina Kosjek (Co-Supervisor)

Year: 2022

Type: Doctoral dissertation

From the moment of conception until death, humans are exposed to chemicals at varying intensities and frequencies. While an individual’s level of resilience is commonly high enough to tolerate these kinds of stressors, specific exposures or genetic predispositions can lower it. Therefore, the assessment of chemical exposure, the development of …

Ostanki bisfenolov v vodnem okolju: pojavnost in kroženje

Author(s): Ana Kovačič (Author), Ester Heath (Supervisor), Tina Kosjek (Co-Supervisor)

Year: 2021

Type: Doctoral dissertation

Bisphenols are a group of industrial chemicals increasingly recognized as contaminants of emerging concern because of their presence in the environment and endocrine disrupting effects. They are used in the production of polycarbonate plastic, epoxy resins and thermal paper, in most cases without restriction. The global exception is bisphenol A, …

Occurrence, fate and removal of pharmaceutical residues in water treatment

Author(s): Tina Kosjek (Author), Ester Heath (Supervisor)

Year: 2009

Type: Doctoral dissertation

The presence of pharmaceutical residues in surface waters is an emerging environmental issue that provides a new challenge to treatment systems for potable water, wastewater and water reuse. Their principle pathways into the sewerage system are twofold: first, after being administered to patients they are normally excreted as various metabolites …