Search Results (3)
Detection of food freshness and pesticides through chemical interaction of liquids or gases with surfaces
Food, water, and sleep form the foundation of human needs, all of which are indispensable. However, unlike sleep, food and water have historically been beyond direct human control. Since ancient times, hunter-gatherers have migrated in search of these essential resources. The advent of agriculture marked a turning point, allowing humans …
Spectroscopic characterization of conformations of short alanine peptides, poly-L-lysine and insulin during formation of amyloid fibrils
The process of protein folding describes the transition by which an unordered polypeptide chain attains its functional native three-dimensional structure. A detailed understanding of the principles which govern the protein folding, such as conformational preferences of amino acid residues, the neighbour residue effect and the solvent effects, remains an important …
Contribution to understanding of the mechanism of amyloid fibril formation and its effects on the cell
The presence of insoluble amyloid aggregates in various human tissues correlates with the development of many human disorders (amyloidoses), including neurodegenerative diseases. Deposition of the aggregated misfolded proteins in the brain, where aggregates can be localized extracellularly or intracellularly, is the main characteristic of Alzheimer's, Parkinson's, Huntington's, prion diseases and …