Viruses, satellite viruses, viroids, virusoids, and satellite nucleic acids (herewith, referred to collectively or in part as ‘viruses’) comprise the virosphere and are perhaps the most diverse and abundant, yet still under-sampled, microbes on Earth. They are primarily regarded as pathogens or parasites of their eukaryotic or prokaryotic hosts. In …
Medicine relies on imaging techniques such as ultrasound, magnetic resonance, computed tomography and histopathological image analysis because they provide valuable data needed for the diagnosis and treatment of diseases and injuries. Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) is often used in research and for the advanced diagnosis and …
According to the World Health Organization (WHO), cancer represents the second leading cause of mortality, with almost 10 million deaths in 2020. A broad spectra of cancer treatments are being developed, among them are metal-based drugs. Consistent with the available data, platinum (Pt)-based chemotherapeutics are still widely used to treat …
Deep cryogenic treatment (DCT) is a type of cryogenic treatment, during which a material is subjected to temperatures below −160 °C. When a metallic material is modified with DCT, changes occur down to the nanoscopic level. DCT induces microstructural changes such as grain size refinement, formation of new grains, movement …
Innate immune system acts as the first line of defence to protect the host against pathogens. The regulation of immune system and inflammatory response is crucial since dysregulated or sustained inflammation leads to pathological conditions, septic shock and tissue damage. Macrophages are innate immune cells that sense pathogens with pattern …
Managers’ commitment to safety has been recognised as a focal concept that can play an important role as organisations strive to improve safety performance and prevent major accidents (Flin, 2003; Flin & Yule, 2004). When management is committed to safety, this shows employees that safety is an important value to …
One of the most commonly used metal materials for the manufacture of biomedical implants are stainless steel and titanium-based alloys. Due to the specific conditions and complex environment in the human body, different strategies have been employed to protect them and improve their functionality in vivo. In this thesis, a …
The inhibitory action of organic compounds, 2-mercaptobenzimidazole (MBI), octylphosphonic acid (OPA) and their binary combinations was studied on aluminium, copper and aluminium alloy (AA) 2024 in chloride environments by ex-situ conventional electrochemical methods and surface-analytical techniques. In addition, the influence of pre-treatment of the metal surface and the choice of …
The thesis addresses a novel representation learning framework, combining neural and symbolic text representations, and demonstrates its utility for tackling diverse natural language processing problems. The proposed approach, avoiding the deficiencies of purely symbolic and purely neural methods, can be applied for the generation of efficient text representations. Its usefulness …
The use of low-cost sensing technologies increasingly used in participatory environmental health studies brings both opportunities and challenges. While previous research mostly focused on technical aspects, this thesis brings participants to the foreground and articulates their experiences. It aims to evaluate if low-cost sensing technologies are fitfor- purpose in environmental …