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Production and characterization of MHC class II invariant chain complex

Author(s): Dušana Majera (Author), Dušan Turk (Supervisor), Jaques Neefjes (Co-Supervisor)

Year: 2012

Type: Doctoral dissertation

Major histocompatibility complex (MHC) class II molecules are polymorphic cell surface glycoproteins expressed only on the surface of the professional antigen presenting cells and they play a crucial role in the adaptive immune responses. MHC class II molecules undergo a very complex maturation process. They are synthesized in the endoplasmic …

Effect of N-glycosylation on plasma glutamate carboxypeptidase function

Author(s): Dejan Suban (Author), Vito Turk (Supervisor), Iztok Dolenc (Co-Supervisor)

Year: 2012

Type: Doctoral dissertation

Plasma glutamate carboxypeptidase (PGCP) is a metalloproteinase. It is able to hydrolyze dipeptides into free amino acids. The enzyme is involved in the release of hormone thyroxin (T4) from Thyroglobulin (Tg), as suggested by thyroid gland studies. Prediction from the primary structure of human PGCP suggests the presence of five …

Controlled synthesis of TiO2 nanoparticles and their application in photovoltaics

Author(s): Dejan Verhovšek (Author), Miran Čeh (Supervisor)

Year: 2012

Type: Doctoral dissertation

Titanium dioxide (TiO2) in nanoparticle form has recently gained a lot of attention, in both the scientific and industrial communities. This is due to the fact that it exhibits various interesting chemical and physical characteristics, for example, a high photocatalytic activity and the absorption of incident UV light. Many applications …

Sonochemical synthesis and characterization of hydroxyapatite/metal-based composite materials for biomedical applications

Author(s): Marija Vukomanović (Author), Srečo Davor Škapin (Supervisor), Dragan Uskoković (Co-Supervisor)

Year: 2012

Type: Doctoral dissertation

A new approach for the synthesis of silver (Ag), platinum (Pt) and gold (Au) nanoparticles and their composites with hydroxyapatite (HAp) is developed via a sonochemical process. The major goal was to design physicochemical properties of material in order to achieve: (i) intensive antibacterial activity and (ii) maximal reduction of …

Parameter Identification in Nonlinear Dynamic Systems with Meta-heuristic Approaches

Author(s): Katerina Tashkova (Author), Sašo Džeroski (Supervisor), Jurij Šilc (Co-Supervisor)

Year: 2012

Type: Doctoral dissertation

The task of mathematical modeling of dynamic systems from observed system behavior, widely known under the name of system identification, breaks down into two subtasks. The first task, referred to as structure identification, is to specify the model structure, i.e., the functional form of the model. In practice, the model …

On-line testing and recovery of FPGA-based systems

Author(s): Uroš Legat (Author), Franc Novak (Supervisor)

Year: 2012

Type: Doctoral dissertation

SRAM-based FPGAs have become an attractive solution for many applications where a short development time, low-cost for low-production volumes, and in-the-field-programming ability are important issues. The flexibility of SRAM-based FPGAs comes from the adoption of a configuration memory that defines the operations of the circuit that the FPGA implements. It …

Moderately porous zirconia ceramics for dental applications

Author(s): Sebastjan Perko (Author), Tomaž Kosmač (Supervisor), Aleš Dakskobler (Co-Supervisor)

Year: 2012

Type: Doctoral dissertation

This doctoral thesis describes the preparation of moderately porous Y-TZP ceramics with improved flexural strength. The main field of application is dentistry, where the elastic mismatch between the Y-TZP material and tooth substance influences the survival rate of fixed partial dentures (FPDs). By introducing porosity into the bulk samples a …

Processing-Dependent Broadband Dielectric Properties of KTaO3 Ceramics, Films and KTa0.6Nb0.4O3 Films

Author(s): Sebastjan Glinšek (Author), Marija Kosec (Supervisor), Zdravko Kutnjak (Co-Supervisor)

Year: 2012

Type: Doctoral dissertation

KTaO3 belongs to the group of incipient ferroelectrics, which are materials important from the fundamental, as well as from the applications, point of view. It is well known in its single-crystal form; however, the processing of technologically interesting ceramics and thin films is a challenging task and knowledge of their …

Development of silicon carbide based implants with improved biocompatibility and mechanical properties

Author(s): Katarina Rade (Author), Saša Novak Krmpotič (Supervisor), Spomenka Kobe (Co-Supervisor)

Year: 2012

Type: Doctoral dissertation

With emerging need for orthopaedic implants and prolonged exposure of organism to implants also problems connected to elution of metal ions that in some cases cause adverse reactions in the human body, emerge. The main aim of our work was therefore to investigate the potential of silicon carbide (SiC) to …

Liquid-crystal microdroplets as optical microresonators and lasers

Author(s): Igor Muševič (Author), Matjaž Humar (Author)

Year: 2012

Type: Doctoral dissertation

This thesis investigates the use of single liquid-crystal droplets as optical microresonators and lasers. We have shown that liquid-crystal droplets can support a number of different optical modes that can be excited by introducing a fluorescent dye in the liquid crystal material and using an external excitation source of light. …