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Plasma sterilization of microorganisms

Author(s): Danijela Vujošević (Author), Miran Mozetič (Supervisor), Uroš Cvelbar (Co-Supervisor)

Year: 2009

Type: Doctoral dissertation

The sterilization efficiency of oxygen plasma was studied. Plasma was created in pure oxygen with an inductively coupled radiofrequency discharge. The discharge power was estimated to about 180 W. Plasma parameters were measured with a double Langmuir probe and a catalytic probe. Plasma parameters depended on pressure in the discharge …

Analysis of bacteria damages caused by treatment with oxygen plasma particles

Author(s): Zoran Vratnica (Author), Miran Mozetič (Supervisor), Uroš Cvelbar (Co-Supervisor)

Year: 2009

Type: Doctoral dissertation

The possible mechanisms for destruction of two types of bacteria with oxygen radicals were studied. Samples consisting of standard ATCC strains of Gram – positive bacteria Staphylococcus aureus and Gram – negative bacteria Escherichia coli were obtained. Bacteria were cultivated according to the standard procedures and fixed on substrates of …

Calculating electrostatic potential around proteins

Author(s): Jure Pražnikar (Author), Dušan Turk (Supervisor)

Year: 2009

Type: Doctoral dissertation

X-rays are diffracted on electron clouds and thereby provide a mean to observe 3-dimensional structure of molecules at atomic level. Using medium resolution diffraction data (2Å and lower) we have shown that averaging of electron density maps generated from sets of randomly distributed atoms and can reduce noise and model …

High-alumina porcelain with improved mechanical and thermal properties

Author(s): Martina Oberžan (Author), Marija Kosec (Supervisor), Janez Holc (Co-Supervisor)

Year: 2009

Type: Doctoral dissertation

The study presents the influence of increasing the amount of β-spodumene (LiAlSi2O6) as Li2O-content flux on phase composition, microstructural evolution and physical properties of high alumina porcelain material containing ~61% of Al2O3. New porcelain compositions based on clays and high amount of calcined alumina were developed with the introduction of …

Monitoring of the product quality in manufacturing industries

Author(s): Jani Kleindienst (Author), Đani Juričić (Supervisor)

Year: 2009

Type: Doctoral dissertation

Unexpected production breakdowns and unpredictable defects in product quality remain critical problems in modern manufacturing systems. Usually occuring by no obvious exterior cause and often during periods of smooth production, they lead to production losses and reduced process availability, which results in lower profit rates. Conventional statistical methods of process …

Role and significance of cysteine cathepsins in different models of apoptosis

Author(s): Ana Petelin (Author), Boris Turk (Supervisor)

Year: 2009

Type: Doctoral dissertation

Programmed cell death is a highly organized process by which multicellular organisms eliminate damaged, superfluous and potentially harmful cells. Apoptosis is the most studied form of programmed cell death. It is characterized by typical morphological and biochemical changes which are a consequence of activation of cysteine proteases, caspases. Apoptosis is …

Development of an alternative approach to membrane protein structure determination based on the analysis of local rotational conformational spaces

Author(s): Aleh Kavalenka (Author), Janez Štrancar (Supervisor)

Year: 2009

Type: Doctoral dissertation

The problem of structure determination of membrane proteins is addressed with a new combination of site-directed spin labelling (SDSL) electron paramagnetic resonance (EPR) spectroscopy and structure modelling of a protein and its conformational spaces. This new approach is aimed at structural characterization of membrane proteins and intrinsically disordered proteins. In …

PURY: A Topology and geometry parameter library for small molecules

Author(s): Miha Andrejašič (Author), Dušan Turk (Supervisor)

Year: 2009

Type: Doctoral dissertation

The number and variety of macromolecular structures in complexes with "hetero" ligands is growing. The need for fast delivery of correct geometric parameters for their refinement, which is often crucial for understanding the biological relevance of the structure, is growing correspondingly. The current standard for describing protein structures is the …

Supervised Descriptive Rule Induction

Author(s): Petra Kralj Novak (Author), Nada Lavrač (Supervisor)

Year: 2009

Type: Doctoral dissertation

The goal of knowledge discovery in databases is to construct models or discover interesting patterns in data. Model construction and pattern discovery are frequently performed by rule learning, as the induced rules are easy to be interpreted by human experts. The standard classification rule learning task is to induce classification/prediction …

Modular gene dynamics and network theory at mesoscopic scale

Author(s): Zoran Levnajić (Author), Bosiljka Tadić (Supervisor), Tomaž Prosen (Co-Supervisor)

Year: 2009

Type: Doctoral dissertation

Complex dynamical systems are often modeled as networks, with nodes representing dynamical units which interact through the network’s links. Gene regulatory networks, responsible for the production of proteins inside a cell, are an example of system that can be described as a network of interacting genes. The behavior of a …