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Comparative View into Protease - Inhibitor Interaction

Author(s): Miha Renko (Author), Dušan Turk (Supervisor)

Year: 2010

Type: Doctoral dissertation

Interactions between macromolecules are the basic events of life. Their characterization is thus a key to understanding the physiology and the underlying specificity of these events. Not only understanding of the final states (where the molecules get closest together), also understanding of the course of approach is mandatory to gain …

Ion Beam Modification of Surfaces in the Nanoscale Domain

Author(s): Barbara Šetina Batič (Author), Monika Jenko (Supervisor)

Year: 2010

Type: Doctoral dissertation

Ion beam sputtering induces morphological as well as compositional changes on the surfaces of ion-sputtered substrates. The surface undergoes kinetic processes, which lead to different morphological details: periodic ripples, substrate-defined etch pits or protuberant structures, roughening and smoothing are some possibilities for surface evolution. The aim of my doctoral dissertation …

Test Infrastructure Design for ADC Cores in System-on-Chip

Author(s): Peter Mrak (Author), Franc Novak (Supervisor)

Year: 2010

Type: Doctoral dissertation

With the advent of System-on-Chip (SoC), intense research efforts are being carried out in order to find efficient practical solutions for testing deeply embedded, mixed-signal cores. Due to restricted access, a built-in self-test (BIST) of mixed-signal cores is in many cases a preferred alternative to a conventional test using external …

Colloidal Interactions and Novel Colloidal Structures in Thin Nematic Layers

Author(s): Uroš Tkalec (Author), Igor Muševič (Supervisor)

Year: 2010

Type: Doctoral dissertation

The thesis presents experimental studies of colloidal interactions and novel colloidal structures in confined nematic liquid crystal using optical tweezers. Liquid crystal colloids are a novel class of composite materials with well-controlled periodic structures in the nanometer and micrometer ranges. Moreover, they also posses novel mechanical, optical and rheological properties, …

NMR Study of Photoisomerization in Bulk and Confined Liquid Crystals

Author(s): Blaž Zupančič (Author), Boštjan Zalar (Supervisor)

Year: 2010

Type: Doctoral dissertation

Deuteron nuclear magnetic resonance was used to study the phase separation behavior of photoisomerizable liquid crystal diheptylazobenzene (7AB). Under UV illumination, the elongated trans molecules are converted to boomerang shaped cis form, creating a binary trans-7AB and cis-7AB mixture. It was demonstrated that the concentration of both components can be …

Role of Cysteine Cathepsins in the Processing, Activation and Inactivation of Perforin

Author(s): Špela Konjar (Author), Nataša Kopitar Jerala (Supervisor), Boris Turk (Co-Supervisor)

Year: 2010

Type: Doctoral dissertation

Natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) recognize virus-infected or malignant transformed cells and destroy them through two independent mechanisms. Apoptotic target-cell death can be triggered by the engagement of death-receptors or by the release of cytotoxic granules. Cytotoxic granules gather at the site of contact between the …

Selenocompounds in selenium-enriched plants determined by spectrometric methods

Author(s): Petra Cuderman (Author), Vekoslava Stibilj (Supervisor)

Year: 2010

Type: Doctoral dissertation

Selenium (Se) has been demonstrated to be an essential trace element for maintenance of animal and human health. Se is incorporated into proteins to make selenoproteins, which are important antioxidant enzymes. The antioxidant properties of selenoproteins help to prevent cellular damage caused by radicals. Radicals are natural by-products of oxygen …

Structural and electrical properties of 0.65PMN-0.35PT thick films on different substrates

Author(s): Hana Uršič Nemevšek (Author), Marija Kosec (Supervisor), Marko Hrovat (Co-Supervisor)

Year: 2010

Type: Doctoral dissertation

A starting powder with the nominal composition 0.65Pb(Mg1/3Nb2/3)O3–0.35PbTiO3 (0.65PMN–0.35PT), which corresponds to the morphotropic phase boundary (MPB) composition, was prepared by mechanochemical activation followed by attritor milling and low-temperature calcination at 700°C. It had a narrow particle size distribution with the median particle size equal to 0.3 μm. From the …

Analysis of results of ecological simulation models with machine learning

Author(s): Aneta Trajanov (Author), Sašo Džeroski (Supervisor)

Year: 2010

Type: Doctoral dissertation

Simulation models are a widely used tool for modelling and simulating systems for which it is hard to obtain real data. However, the simulation models are usually complex and it is not an easy task to induce new knowledge and find relationships and dependencies among different parts (parameters, processes, modules) …