Solving real-life optimization problems numerically is often very time demanding, because of high complexity of the simulations that are usually involved. Solving such problems becomes highly impractical for this reason and can even lead to use of less complex and also less accurate models. Fortunately, evolutionary algorithms, often used in …
Disertacija se z novo kombinacijo metod mestno specifičnega označevanja (SDSL), elektronske paramagnetne resonance (EPR) in modeliranja strukture proteina ter njegovih konformacijskih prostorov loteva problema določevanja struktur proteinov. Nov pristop je namenjen predvsem strukturni karakterizaciji membranskih in intrinzično neurejenih proteinov. V prvem delu disertacije so predstavljene izboljšave analize EPR spektrov s …